Santamaggiore Inn guest house Rome enjoys a fine central location just moments away from the city’s main train station and bus terminal, Roma Termini, where the city’s metro lines also converge. With the historical city centre on the doorstep and everything within easy reach on public transport, you’ll rarely need to splash out on a taxi when staying at our quality Rome guest house.


In the immediate vicinity of the Santamaggiore Guest House are two of central Rome’s most vibrant and characteristic neighbourhoods in Monti and San Lorenzo, while major landmarks just moments from our door include the Basilica of Santa Maria Maggiore, the Colosseum and the National Opera Theatre. You’ll find restaurants and bars for all budgets and styles within easy reach on foot.


The Santamaggiore Inn in Rome and our sister properties all offer a competitive airport transfer service - simply enquire when booking online here via our official website. Regular transport links connect both airports to Roma Termini during the day and our Rome city centre accommodation is just a short walk from the train station. Taxis charge a fixed rate printed on the car door.


Public transport in Rome is cheap and the metro in particular is fast and reliable until around midnight. Guests at Santamaggiore can reach such famous places as St Peter’s and the Vatican Museums including the Sistine Chapel; the Colosseum and Roman Forums, the Spanish Steps, Piazza del Popolo and the Olympic Stadium within a matter of minutes from our hotel door.


  • Basilica S. M. Maggiore
  • Roma Termini
  • Baths of Diocletian
  • National Opera Theatre
  • Piazza Vittorio
  • San Lorenzo
  • Monti
  • Colosseum
  • Colle Oppio


  • Colosseum
  • Roman Forums
  • St Peter’s & Vatican
  • Olympic Stadium
  • San Giovanni
  • Piazza Venezia
  • Torre Argentina
  • Pantheon
  • San Paolo